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Further studies are necessary to investigate repeated and longitudinal measures in COs for addition electrophysiological endpoints as well as measuring other markers including mitochondrial biogenesis and calcium regulations

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It is knowing which patient needs a GLP-1 and which one needs a workup, how to titrate through the nausea window without losing the patient, how to protect lean mass during rapid loss, how to screen for the contraindications that matter, and how to tell a patient honestly what an adjunct will and will not do for them

Rafalski M, Ortiz A, Rockwell A, Van Ginkel LC, Lear JD, DeGrado WF, et al