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The occurrence of hyperactivated platelets and fibrinaloid microclots in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)

During the senescence of RBCs and where energy yield is low, PS is externalized to act as an eat me signal to be engulfed by macrophages

Manokawinchoke J, Sumrejkanchanakij P, Pavasant P, Osathanon T (2017) Notch signaling participates in TGF-beta-Induced SOST expression under intermittent compressive stress