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Further analyses have revealed pronounced gut microbial dysbiosis in cirrhotic patients with hepatic encephalopathy (HE), marked by increased abundances of bacterial families such as Alcaligenaceae, Porphyromonadaceae, and Veillonellaceae, as well as genera including Enterococcus , Megasphaera , and Burkholderia (498)

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2D, Fig

Butyrate ameliorated ferroptosis in ulcerative colitis through modulating Nrf2/GPX4 signal pathway and improving intestinal barrier

In addition, at least three gain-of-function strains that ectopically producing individual Chi proteins survived in human serum similar to the CihC- and HcpA-producing strains, respectively 15,16 (Fig