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Together, HO-1 and NQO1 activity lowers the intracellular ROS levels, preserves mitochondrial membrane potential, and reduces the release of DAMPS such as cardiolipin and mitochondrial DNA, both potent activators of NLRP3 [67], as shown in Fig

Ferroptosis is an iron-dependent form of cell death characterized by intracellular lipid peroxide accumulation and reactive oxygen species (ROS) imbalance

However, current findings are limited mainly to chemical compositional analyses, and practical parameters such as sensory acceptance, consumer satisfaction, and product stability are not adequately addressed

The latter may present even in the absence of hematological findings and this situation makes the diagnosis of PA extremely difficult