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The field of peptide therapeutics is rapidly evolving, with new peptides gaining FDA approval

As a potential therapeutic target for glioma, recent studies have shown that RAS-selective lethal 3 drives iron death through NF-B pathway activation and GPX4 depletion in GBM (63)

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15,16 While more studies are needed to identify the incidence and prevalence of vitamin B 12 deficiency in this subset of patients, screening for subclinical B 12 deficiency should be a consideration in patients who have received long-term acid-suppression therapy

doi: 10.3168/jds.2019-17125 246 LiYLiuJXXiongJLWangYMZhangWXWangDM