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233 In a randomized controlled trial, 102 people with fibromyalgia received daily treatment with either 500 mg of oral acetyl-L-carnitine twice daily plus 500 mg of intramuscularly injected acetyl-L-carnitine or oral and intramuscular placebos for two weeks

The collection of extended data from clinical trials and subsequent follow-up studies to evaluate the safety and efficacy of TE interventions holds significant importance

In the past twenty years, and mainly by repurposing drugs use, molecules have been identified but to date, clinical trials display moderated efficiency

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Similarly, mutations in the SCO2 gene impair mitochondrial function and can cause cardiomyopathy, underscoring the critical role of copper delivery systems [181]