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The FASEB Journal, 20 (2), 377-379.

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Its especially important for producing nitric oxide, which widens blood vessels to support blood flow, promoting immune function and aiding cellular communication

Those exceptional Qualifying variants most likely to be disease related were categorized as Key Qualifying variants, and additionally met at least one of the following categories: Pathogenic or Likely Pathogenic (P/LP) variants: These variants are listed in ClinVar 6 as being either pathogenic (P) or likely pathogenic (LP) for disease

doi: 10.1007/s00484-014-0829-1 73