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doi: 10.1038/s41577-020-00478-8 249 MittalMSiddiquiMRTranKReddySPMalikAB

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The first phase, or oxidative phase, consists of two irreversible oxidations that produce NADPH

Our study demonstrated that methylated UBE2m increases the neddylation level and protein stability of NEDD4

To further elucidate the molecular mechanism of RRM2 regulation of cell cycle, we examined the expression levels of cell cycle-related proteins (Cyclin A2, Cyclin E2, c-MYC, Cyclin D1, CDK2) in TPC-1 cells by Western blot