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Semaglutide and tirzepatide have FDA approved uses, while some other peptides discussed online or in wellness settings are not FDA approved drugs and may involve added safety and regulatory considerations

Finally, although HG106 was recently identified as a SLC7A11 inhibitor (Hu et al., 2020), whether it can act as a FIN remains to be further examined (so far, all other SLC7A11 inhibitors can induce ferroptosis)

Exp Neurol 209:213223 Wang L, Yang HJ, Xia YY, Feng ZW (2010) Insulin-like growth factor 1 protects human neuroblastoma cells SH-EP1 against MPP+-induced apoptosis by AKT/GSK-3beta/JNK signaling

Eosinophilia in blood or tissue or both is associated with helminthiasis, allergic hypersensitivity, and other pathological conditions

Wang et al., 2022), and functional short peptides such as WP9QY (W9) (Zhao et al., 2024b) and PPFLMLLKGSTR (Sun et al., 2024) to form composite hybrid hydrogels that improved the RADA16 hydrogel hydrophilicity and mechanical strength while imparting it with new biological activity