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As mentioned above, a number of compounds or drug formulations have been investigated with regard to inhibiting cysteine metabolism, either by targeting H 2 S-synthesising trans-sulphuration pathway enzymes (e.g

Harrisons principles of internal medicine, 17th edn

102 One double-blind, placebo-controlled trial evaluated NAC in children and adolescents with Tourette syndrome (tics), which is commonly associated with OCD, but found no benefit of 2400 mg per day for 12 weeks versus placebo

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Despite showing a less potent vasorelaxant effect than sildenafil (EC 50 = 0.05 M), their vasorelaxant effect was more selective for pulmonary arteries over the thoracic aorta