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Determination of some lipid profile parameters in induced hyperthyroid rats as well as those treated with folic acid and / or vitamin C as compared to control (mean SEM) Graph 2 a represents the adrenal total protein, 2-b represents the adrenal MDA, 2-c represents the adrenal reduced glutathione, 2-d represents the adrenal catalase, 2-e represents the adrenal nitric oxide in induced hyperthyroid rats as well as those treated with folic acid and / or vitamin C

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At the same time, ROS can interfere with the activity of key enzyme systems involved in redox regulation within the endoplasmic reticulum, such as glutathione peroxidase (GPx) and thioredoxin reductase (TrxR), causing an imbalance in its redox potential and further weakening protein folding capacity

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