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the study subjects were not clearly diagnosed with DOR/POR, or the study population was highly heterogeneous

People who follow vegetarian or vegan diets may be at higher risk of inadequate intake and may consider fortified foods or supplements after consulting a healthcare provider

Consistent with these observations, in vivo metabolic profiling in rats has revealed that EC undergoes extensive mono- and di-methylation, often followed by subsequent glucuronidation or sulfation, resulting in the formation of structurally diverse phase II conjugates (Shang et al., 2017)

These statements have not been evaluated by the Food and Drug Administration