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Aromatization: Testosterone to Estradiol A portion of testosterone is converted to estradiol (a form of estrogen) by the aromatase enzyme, primarily in fat tissue

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Mayo Clin Proc 2015

The three compounds all preserve that synergy

A meta-analysis that included a total of 1,878 cases of BC found that aberrant activation of Wnt-catenin was especially common in TNBC compared to other types of breast cancer (177)