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Oncogenic RIT1 mutations not only activate canonical RAS/MAPK and PI3K/AKT pathways but also modulate nuclear factor, erythroid 2 like 2 (NRF2) target expression, markedly increasing cellular susceptibility to ferroptosis inducers (33)

Whittaker et al., 2017

Utilizing machine learning for predicting drug release from polymeric drug delivery systems

Researchers believe that the main cause of this condition involves a disruption in the immune systems regulation, leading to the destruction of melanocytes