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Although the contribution of different factors in developing radioresistance in RC cells is not fully understood, studies by various groups have shown that intrinsic radioresistance properties, lower apoptosis induction following RT, and functional changes in protooncogenes and tumor-suppressor genes play crucial role in developing RT resistance

Abbreviations AA : Amino acid ANOVA : Analysis of variance AUC : Area under the curve BCAA : Branched-chain amino acid BMI : Body mass index ESI : Electrospray ionization IFP : Infrapatellar fat pad KOA : Knee osteoarthritis LDA : Linear discriminant analysis LI : Level of identification OA : Osteoarthritis PLS-DA : Partial least squares discriminant analysis QC : Quality control RA : Rheumatoid arthritis ROC : Receiver operating characteristic SE : Standard error SF : Synovial fluid TKA : Total knee arthroplasty TOF : Time-of-flight VIP : Variable importance in projection References Kontny E, Zieliska A, Ksiopolska-Orowska K, Guszko P (2016) Secretory activity of subcutaneous abdominal adipose tissue in male patients with rheumatoid arthritis and osteoarthritis association with clinical and laboratory data

Rather than running each compound separately, investigators studying joint stress, tendon overload, or wound-repair models can work from a single pre-verified formulation with documented purity across all four components

Epidemiology 10:370375

Effect of Glutathione Infusion on Leg Arterial Circulation, Cutaneous Microcirculation, and Pain-Free Walking Distance in Patients With Peripheral Obstructive Arterial Disease: A Randomized, Double-Blind, Placebo-Controlled Trial 23