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This process is governed by the angiogenic switch mechanism, where dynamic equilibrium between pro-angiogenic (e.g., VEGF/VEGFR axis) and anti-angiogenic factors (e.g., p53-mediated pathways) determines neovascularization outcomes (95)

The Phase 2 data showed weight loss curves that had not plateaued, meaning longer treatment durations could push the numbers even higher

NMDA receptor activity downregulates KCC2 resulting in depolarizing GABAA receptor-mediated currents

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Moreover, it is important to note that TRAb is a specific autoantibody, not typically produced during standard immune responses