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Hayashi S, Nakamura T, Motooka Y, Ito F, Jiang L, Akatsuka S, et al

Systematic review and meta-analysis of the efficacy of N-acetylcysteine in the treatment of acute exacerbation of chronic obstructive pulmonary disease

Multiple meta-analyzes have attempted to consolidate these findings: A systematic review found pooled IBS incidence rates of 12% among COVID-19 patients Cross-sectional studies report prevalence rates of 13% , whereas longitudinal studies show rates of 16% The subtypes distribution shows IBS-D (diarrhea-predominant) at 5% , IBS-C (constipation-predominant) at 2% , and IBS-M (mixed) at 1% The wide variation in reported figuresfrom as low as 0.17% to as high as 20%stems from differing diagnostic standards, with Rome IV criteria yielding substantially lower prevalence estimates than Rome III

weight outcomes were modest and inconsistent, and development for obesity treatment was not continued

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