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In thesis, obesity-related metabolic dysfunction could hinder the expected epigenetic responses, potentially due to factors such as increased folate utilization, higher urinary excretion, blood volume dilution, tissue distribution differences, and endocrine alterations [41, 42]

Study findings revealed that raw white garlic consumption was associated with reductions in the risks of chronic diseases, including cancers (especially liver and esophageal cancers), prehypertension, depression (especially in women), and the recently diagnosed nonalcoholic fatty liver disease (NAFLD)

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Many of the oxidative stress biomarker profiles are altered in ALS bio-samples and animal models, where it has been observed that oxidative stress promotes the aggregation of acetylated TDP-43 which hinders RNA binding and encourages the accumulation of insoluble, hyperphosphorylated TDP-43 species