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On the other hand, STING1-mediated autophagy and MFN1 (mitofusin1)-MFN2-dependent mitochondrial fusion can increase ferroptosis sensitivity to various stimuli, including GPX4 inhibitors [186]

BAL fluid and intracellular GSH pathways correlate with HAEC T2-associated gene expression To determine whether these in vitro findings were reflected ex vivo, BAL fluid GSSG levels were compared to fresh HAEC expression of T2-related genes from 2 different RNA-Seq databases (SARP3 and IMSA), which were harmonized and merged as outlined in the Methods (Table 3)