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We propose that researchers conduct a prospective cohort study with a larger sample size to determine the exact effects of DTG and ATV/r on serum uric acid and hsCRP levels

Among its known binding partners are E3 ligases TRIM27 and RNF41, and the deubiquitinases USP7 and USP8, which it recruits to regulate the ubiquitination and stability of diverse targets (Tacer and Potts, 2017

Through activation of the Nrf2antioxidant response element (ARE) signaling axis, GSH upregulates cytoprotective enzymes such as heme oxygenase-1, glutathione peroxidase, and NAD(P)H quinone oxidoreductase-1, thereby enhancing cellular resistance to oxidative injury [10]