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(11) This has led to the hypothesis that exogenous FOXO protein, such as FOXO4-DRI peptide, may help regulate optimal levels of FOXO proteins, thereby preventing or alleviating the progression of any NDDs associated with this mechanism

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For example, monosodium glutamate (MSG) and aspartame are food additives that can cause excessive stimulation of nerve fibers, possibly contributing to increased pain signaling