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The primary epigenetic alterations include noncoding RNAs, DNA methylation, histone modifications, RNA modifications and chromatin remodelling

Nevertheless, other inhibitors, including GLS1/GLS2 inhibitor compound 968 and G6PD inhibitor 6-aminonicotinamide (6-AN) were failed to induce the above alterations in VRK2-KO and VRK2-KD cells (Fig

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