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Figure 1 2 Literature search strategy To ensure a comprehensive and rigorous synthesis of the current knowledge regarding the gut-bone axis, a thorough literature search was conducted

People on vegan or strict plant-based diets need a reliable source from fortified foods (nutritional yeast, fortified plant milks, certain breakfast cereals) or a supplement

It follows a precise cycle with three phases: anagen, catagen, and telogen

PD, Parkinson's disease

Key considerations from available evidence: No direct hormonal mechanism linking tirzepatide to menstrual disruption has been identified Metabolic improvements (reduced insulin resistance, decreased androgens) may benefit women with PCOS The magnitude and rapidity of weight loss correlate with likelihood of temporary menstrual changes Long-term data on reproductive outcomes remain limited Healthcare providers should counsel women of reproductive age about potential menstrual changes when initiating tirzepatide