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Nearly all quinolone antibiotics in use are fluoroquinolones, which contain a fluorine atom in their chemical structure and are effective against both Gram-negative and Gram-positive bacteria

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People with a prior history of gastrointestinal problems and aged individuals are more likely to suffer from intense stomach cramps and severe diarrhoea after taking high doses of vitamin B. Most people are able to get enough vitamin B12 from their diets, however, occasionally when running low, supplements or B12 injections may be recommended