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Key Takeaways Genetic dark circles under the eyes often appear because of thin skin, deep tear troughs, or extra pigment beneath the eyes

The following types are those most commonly reported: Central Nervous System CNS manifestations are excitatory and/or depressant and may be characterized by lightheadedness, nervousness, apprehension, euphoria, confusion, dizziness, drowsiness, tinnitus, blurred or double vision, vomiting, sensations of heat, cold or numbness, twitching, tremors, convulsions, unconsciousness, respiratory depression and arrest

For individuals struggling with B12 deficiency, oral supplements may not always offer sufficient remediation

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The most common reported effect is a 3060-second sting from the copper-peptide complex