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The frequency of fibromyalgia increases significantly where patients have one of several chronic diseases, such as inflammatory or degenerative arthritis, chronic heart failure, chronic liver or kidney disease, among others

Safety, tolerability, and preliminary efficacy of an IGF-1 mimetic in patients with spinal and bulbar muscular atrophy: a randomised, placebo-controlled trial

An animal study (Liu et al., 2023) showed that downregulation of CLDN5 under hypoxic conditions could significantly activate the expression of ferroptosis-related genes and inhibit the expression of SLC7A11, inducing BBB disruption