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Description

While injectable glutathione provides exogenous glutathione directly, concurrent NAC supplementation supports the body's endogenous glutathione production capacity

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In particular, lysosomal cholesterol accumulation may predispose to APAP hepatotoxicity by a dual mechanism involving the impairment of mitophagy in hepatocytes and the disruption of TLR9 trafficking in LSEC

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Excessive -synuclein aggregation in PD further exacerbates autophagy dysfunction while contributing to neuroinflammation

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Ledo et al., 2016), in agreement with the existence of common pathological features between AD and major depressive disorder (Torrisi et al., 2019)

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