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Objective: Use data from a prospective, multi-center adult cohort of AATD ZZ subjects with protocol enrollment liver biopsies to identify the prognostic value of clinical markers and biopsy for the development of severe liver disease outcomes

Although the functions of AIMPs are not fully understood, increasing evidence indicates that these scaffold proteins usually exert tumor-suppressive activities

Applications include stroke recovery research, neurodegenerative disease studies, and cognitive aging investigations

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