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On the other hand, infiltrating CD8 + T cells also displayed significantly much higher levels of lipid ROS than splenic counterparts (Figure 1, D and E), suggesting that the balance between GSH and lipid ROS may contribute to their function

Several transcription factors such as activator protein (AP-1), nuclear factor kappa B (NF-B), and predominantly the nuclear factor erythroid 2related factor 2 (Nrf2) are involved in the induction of antioxidant enzymes

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