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Safety is dose, delivery, and patient selection dependent, so implement mitigation measures including baseline screening, slow dose escalation, and monitoring for immune reactions or aberrant tissue growth

Computational models incorporating these disruptions revealed that SHANK3 haploinsufficiency reduces AMPA and NMDA receptor mobility at postsynaptic densities, impairing long-term potentiation (LTP) and glutamatergic signaling fidelity [126]

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See a dermatologist if you notice light-brown-to-black patches on your skin, especially if they appear suddenly

1 It also slows gastric emptying, so food stays in your stomach longer, reducing hunger and calorie intake