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[DOI] [PubMed] [Google Scholar] 113.Costanzo P.R., Suarez S.M., Kozak A.E., Knoblovits P

ALA-100 refers to the prevention mice who received 100 mg/kd/bw/day of ALA

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Rare variant analysis has revealed that loss-of-function mutations within activating transcription factor 4 (ATF4), a transcription factor responsible for the upregulation of serine synthesis under conditions of serine starvation, are associated with higher risk for PAH, which further suggests serine is closely related PAH