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doi: 10.1038/s41467-024-50077-7 339 LuZMcBreartyNChenJTomarVSZhangHDe RosaGet al

Naringenin, a flavanone compound found in grapefruits and other citrus fruits, could reduce ATF6 nuclear translocation and activity, by which it decreases the expression of ER stress markers while enhances the expression of cholesterol efflux genes (ABCA1, ABCG1 and LXR)