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These include both immune-stimulating and immune-suppressing peptides, depending on the therapeutic application

Other strategies include dopamine agonists that bind to the dopamine receptors in the pituitary gland and block the secretion of prolactin and GH

Interestingly, despite GH deficiency and low serum IGF-I concentration, they exhibit normal levels of testicular IGF-I[119]

Issues raised in academic and consumer reviews include irritation in cosmetic-formulation use, very wide variation in product quality across the unregulated marketplace, formulation-stability problems, ingredient-interaction concerns, and a thin clinical-trial evidence base relative to the strength of consumer marketing claims

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