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Caveolin-1 (CAV-1) is the main protein component of caveolae, associated with TGF- receptors localization, trafficking and degradation, and plays an important role in the pathogenesis of different fibrosing diseases

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In addition, traditionally it was thought that Met synthesis in plants requires transport of homocysteine from plastids to the cytoplasm, as the activity of the last enzyme of the biosynthetic pathway, MS, was found in this compartment only (Wallsgrove et al., 1983