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doi: 10.1016/j.phrs.2018.04.023 80 RyszJFranczykBawiskiJOlszewskiRCiakowska-RyszAGluba-BrzzkaA

The second enzyme of GSH synthesis, GSH synthase (GS) is also regulated in a coordinated manner as GCL subunits and its up-regulation can further enhance the capacity of the cell to synthesize GSH

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After considering this issue further since the FY 2022 rulemaking, we do not believe that the current general correlation between the two precludes the ability of this data over time to reflect market-based pricing for at least some services

These diabetes-specific results mirror the pattern seen with CagriSema in REDEFINE 2, though direct comparison requires caution because the trial populations and designs differed