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PMID: 39159301 Adv Sci (Weinh)Inhibition of CARM1-Mediated Methylation of ACSL4 Promotes Ferroptosis in Colorectal Cancer

However, the mechanism beneath the effect of GSH depletion-induced oxidative stress in RPE cells and the subsequent RPE damage is not well established

These results agree with a previous study showing that patients with KRAS mutations usually have an inflammatory TME and higher tumour immunogenicity, leading to a better response to PD-1/PD-L1 inhibitors 205