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Second, it inhibits aromatase, the enzyme that converts testosterone to estrogen

J Funct Foods (2018) 42:32738

As a further suggestion of a cooperative role between ROS and STAT1 activation, in NOX-deficient diabetic mice the reduced ROS levels were found to impair STAT1 activation, and to increase STAT6 activation, thereby promoting a M2 signature during diabetes progression (133)