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22(1): 4654 Jiang X, Williams KM, Liauw WS, et al

Studies have demonstrated that phosphorylation of Drp1 at Ser616 can promote the recruitment of Drp1 to mitochondria, while AMPK agonists can prevent this process [203]

Magnesium acts as a critical cofactor in ATP stabilization and enzyme activation across numerous metabolic pathways

It is particularly important to note that for PLWH presenting with unexplained cognitive impairment or neurological symptoms, even if plasma viral load is controlled, CSF HIV RNA quantification and drug resistance genotype testing should be considered to rule out the possibility of CSF viral escape (175)

It is important to bear in mind that the temperature during the trek is cold at night and hot during the day