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Despite the precise etiology of PE remaining unclear at present, increasing evidence suggests an association between PE and an imbalance in inflammation, contributing to endothelial dysfunction

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CRISPR-Cas9 deletion of -cell 2A -adrenergic receptor in INS-1E cells reduces DAs ability to inhibit GSIS in the KO cells

Electronic supplementary material The online version of this article (doi:10.1186/s12970-015-0067-x) contains supplementary material, which is available to authorized users

The authors concluded that 10 mg/kg every 12 hours would result in theophylline concentrations in the therapeutic range