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The impact of mitochondrial dysfunction on ovarian aging

Planta Med 75(6):575580

Adv Exp Med Biol 500:1-10, 2001

TGF- signaling from receptors to Smads

Persistent elevations in blood glucose activate several interconnected biochemical and molecular pathways, including the polyol pathway, the formation of AGEs, activation of protein kinase C, the hexosamine biosynthetic pathway, excessive oxidative stress, and epigenetic modifications