nadph-dependent glutathione reductase mechanism Frontiers Stimulation of de novo glutathione

The transferrin receptor CD71, normally expressed on the basolateral side of enterocytes, is overexpressed on the luminal side of the intestinal epithelium in CD patients during the acute phase of the disease, leading to an apical-to-basal retrotranscytosis of gliadin peptides complexed with secretory IgA [47]

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doi: 10.1016/j.lfs.2011.05.018

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In a human study, Meriva significantly improved curcumin's plasma levels compared to standard preparations (Anand et al