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To guide commencement of Auranofin treatment in 018Z experiment, leukaemia burden was assessed after 4 days using bioluminescence imaging by injecting mice subcutaneously with 200 L (15 mg/ml) D-Luciferin (Promega, # E1601), anesthetising them with 23% isoflurane, and imaging them on an IVIS Spectrum (PerkinElmer)