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Gonadotropin releasing hormone agonists, such as goserelin, are employed to induce a hypoestrogenic state by initially stimulating and then downregulating pituitary hormone secretion, whereas gonadotropin releasing hormone antagonists, directly block receptor binding for a more rapid onset of action (5)

elegans as an excellent model for studying the lipid metabolism, more genes and substances with body fat regulatory functions will be screened and studied in the future