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[DOI] [PubMed] [Google Scholar] 84.Kliewer S.A., Umesono K., Mangelsdorf D.J., Evans R.M

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Methionine is an essential amino acid obtained from dietary protein and serves as the starting point of the methylation cycle

Collectively, these findings support a bidirectional relationship in which sleep promotes mitochondrial redox homeostasis, while mitochondrial oxidative status shapes sleep quantity, quality, and circadian stability, processes with broad implications for aging and neurodegenerative diseases

ERYTHROCYTE ISOLATION Red blood cells were isolated from whole blood by density gradient centrifugation with FICOLL-Paque (GE Healthcare, 17-440-02)