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381 Similarly, RTK inhibitors targeting PDGFR (e.g., olaratumab and crenolanib) and c-KIT (avapritinib) show promising BBB penetration but are hindered by resistance mechanisms

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Blood 130(10):12091212 Choi R, Lee MN, Kim K, Baek SY, Kim TJ, Hong SN et al (2020) Effects of various genetic polymorphisms on thiopurine treatment-associated outcomes for Korean patients with Crohns disease