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Graphical Abstract Similar content being viewed by others Introduction Long-term exposure to air pollution is associated with increased risk of cardiopulmonary and neurological diseases, cancer, and overall mortality [1]

During fermentation, elevated amount of polyunsaturated fatty acid and reduced saturated fatty acid content were also observed (Vieira et al., 2017)

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Additionally, itaconate inhibits CD8 + T cell proliferation and their anti-tumor immune function by suppressing aspartate/serine synthesis (329)

PBMC pellets were resuspended in Roswell Park Memorial Institute (RPMI)-medium without additives