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One of the strategies for the treatment of RA is to convert traditional Treg cells into Foxp3 + Treg cells with stable inhibitory function, and reduce the related inflammation caused by the conversion of Treg cells into Th17 cells (199, 200)

Wang X, Qian S, Wang S, et al

Regulation of energy metabolism through modulation of acyl CoA:CoA ratio Free (nonesterified) CoA is required as a cofactor for numerous cellular reactions