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Do not stop prescribed B12 supplementation without consulting your GP, as untreated deficiency can cause serious neurological harm

Commenters asserted that the proposed attestation requirement goes well beyond the intent of helping patients understand prices, veering instead into revealing trade secrets that do not meaningfully help a patient estimate their out-of-pocket cost

Your care team can suggest a sensible cadence based on your plan and how you respond, and will keep your expectations grounded throughout

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Estimating treatment effects: accounting for intercurrent events and handling missing data The ICH recommends the use of estimands in clinical trials [3]