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Description

The protocol had been implemented with the default parameters except for Force field (CHARMm) and Ligand partial charge Method (Momey-Rone) 31,32

IGF-1 LR3 Side Effects While IGF-1 LR3 administration is considered to be relatively safe at proper dosages, excessive levels of IGF-1 in the body can cause side effects, mainly due to the impact on insulin and glucose levels

Candidate biochemical markers were selected based on pilot study results and for citations already-outlined in the Section Introduction. Standardized collection methods, protocols, and citations are documented in Sections S4 and S5 in Supplementary Material