glutathione sepharose affinity column Resin HOOK GST Protein Spin Purification (Yeast) affinity purification of a glutathione-s-transferase

Cell 149: 2235 Horiuchi D, Anderton B, Goga A (2014) Taking on challenging targets: making MYC druggable

Cell 69 , 581593.e587 (2018)

All treatment decisions are based on clinical suitability and patient safety

DOI: 10.1016/0092-8674(93)90415-M IGF-1 Axis and Anabolic Signalling Landmark studies establishing the GH/IGF-1 axis including the somatomedin hypothesis refinements by LeRoith, Laron, and colleagues defined IGF-1 as the primary mediator of GHs anabolic and growth-promoting effects, confirmed the liver as the primary source of circulating IGF-1, and established the research framework for GH deficiency and GH replacement biology that underpins current pre-clinical GH axis research

Additionally, Mendelian randomization studies have found that higher circulating glutamine is associated with reduced IPF risk, suggesting a protective role [132]